Developed based on a thorough review of the scientific evidence, NutraOrigin’s Energane formula includes only ingredients with documented efficacy and safety, and contains no artificial colors, flavors or preservatives. The ingredients described below will give you a better understanding of how Energane helps boost your energy.*

Cordyceps Sinensis Extract
Cordyceps sinensis (mycelia) is a botanical ingredient that has been used in Traditional Chinese Medicine for hundreds of years as a tonic for enhancing longevity, vitality and endurance.* (1) It benefits individuals by supporting their capacity to function at a higher level of activity.*

Several studies have shown that Cordyceps enhances cellular energy production and oxygen supply.* One double-blind, placebo-controlled investigation reported a noticeable decrease in occasional fatigue.* Another showed that shortness of breath was improved and fatigue was minimized.* (2)

Rhodiola Rosea Root
Rhodiola rosea hails from Eastern Europe, where it was intensely studied by the Soviets in an effort to improve the physical performance of their Olympic athletes. It is considered an adaptogen, meaning an herb that helps the body adapt to all kinds of stress.*

Rhodiola Rosea root has long been used to diminish occasional fatigue.* More recently, it has been observed to increase the body’s natural resistance to chemical, biological and physical stressors.* (3) Several double-blind, placebo-controlled human clinical trials have proven that Rhodiola boosts the body’s physical and mental work capacity and has a pronounced anti-fatigue effect.* (4,5,6,7) It has also been shown to decrease levels of cortisol, a stress hormone.* (7)

Ashwagandha
Ashwaganda is an Indian herb that plays a central role in the herbal tradition of Ayurveda. It is considered an adaptogen, meaning an herb that helps the body adapt to all kinds of stress.* When the body successfully manages stress, mental and physical performance are increased, while fatigue is decreased.*

There is speculation that occasional fatigue may be caused by oxidative stress. A stress test conducted on mice found that various antioxidants, including ashwagandha, increased energy levels depleted by exertion.* (8) In fact, animal studies have consistently found that ashwagandha combats the effects of occasional stress and has a rejuvenating effect.* (9,10,11,12)

Schisandra Extract
Another favored herb of Traditional Chinese Medicine, schisandra is mentioned in the ancient text the Divine Husbandman’s Classic of the Materia Medica (circa 1^st century BC), where it is said to increase energy and relieve fatigue.* In Russia, schisandra has been researched as an adaptogen, enhancing the body’s natural capability to adapt to all kinds of stress.*

Studies on human subjects — including athletes, telegraphists, airline attendants and soldiers — have shown that schisandra increases stamina, reduces post-exercise recovery time, decreases occasional fatigue and improves concentration.* (13) Race horses treated with schisandra have demonstrated enhanced physical performance and reduced recovery time.* (13)

Astragalus Root Extract
Astragalus is an herb featured in many traditional Chinese formulas. Chinese society has valued astragalus for its adaptogenic, stress-fighting properties and its capacity to support the immune system.* In Traditional Chinese Medicine, astragalus is said to “strengthen the qi,” meaning it nourishes the body’s energy reserves.*

Astragalus appears to boost energy levels in people who experience occasional fatigue, possibly by improving immune function.* (15)

Magnesium Aspartate and Potassium Aspartate
Magnesium and potassium are essential minerals. No other minerals are more concentrated within the cells. (16) It’s not a coincidence that magnesium stores are concentrated within the brain, heart, liver and kidneys — organs with the highest energy demands — because the mineral plays an important role in energy production.* Potassium is an electrolyte, meaning a substance that can conduct electrical impulses in the body.* Therefore, low levels of either magnesium or potassium can contribute to occasional fatigue.*

A group of researchers conducted a case-control study to compare subjects’ magnesium stores with their energy levels. The results showed that people who complained of feeling tired had lower magnesium concentrations in their blood than people who felt energetic.* (17) The same researchers then conducted a randomized, double-blind, placebo-controlled trial to test the theory that magnesium supplementation would improve energy levels. It did: people who received magnesium supplements claimed higher energy levels and improved emotional states than those who took placebo pills.* (17) Research indicates that getting enough potassium is important while taking magnesium.* (18,20)

L-Carnitine
Carnitine is an amino acid derivative. Its role in the body is to shuttle long-chain fatty acids into the mitochondria of cells, where they can be burned for energy.* (21)

Two human studies suggest that carnitine supplementation improves energy levels in people suffering from occasional fatigue.* (22,23) In fact, low blood levels of carnitine have been correlated with low energy in human subjects.* (24)  Additionally, two multicenter, controlled clinical trials have found that supplementation with L-carnitine increases exercise tolerance.* (25,26)

Coenzyme Q₁₀
Coenzyme Q₁₀, also known as ubiquinone, is a vitamin-like substance that is present in most human cells and that participates in the body’s production of energy.* CoQ₁₀ is a component of the electron transport chain and partakes in aerobic cellular respiration, producing energy in the form of ATP.* (27,28) Organs with the highest energy requirements, such as the heart, liver and kidneys, also have the greatest CoQ₁₀ concentrations.* (29)

Coenzyme Q10 benefits exercise capacity, as demonstrated by a study of Finnish top-level cross-country skiers.* CoQ10 supplementation significantly improved all measured indexes of physical performance, and 94% of the athletes taking CoQ10 felt it had improved their performance and recovery time, compared with only 33% of those in the placebo group.* (30)

Nicotinamide Adenine Dinucleotide
Nicotinamide Adenine Dinucleotide (NADH) is a coenzyme — the active, usable form — of vitamin B3 (niacin). It participates in the electron transport chain, which generates a large amount of physical energy in the form of ATP.* As an electron donor, each unit of NADH can produce three units of ATP.* (31)

The results of a randomized, double-blind, placebo-controlled pilot study indicated that NADH may be valuable for alleviating occasional fatigue.* (32)

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