Developed based on a thorough review of the scientific evidence, NutraOrigin’s Digestalin formula includes only ingredients with documented efficacy and safety, and contains no artificial colors, flavors or preservatives. The ingredients described below will give you a better understanding of how Digestalin supports healthy digestion. *

Bromelain
Bromelain (bromelin) is a collection of proteolytic (protein-digesting) enzymes naturally present in pineapple. Not surprisingly, pineapple has been used by Central and South American cultures for hundreds of years to promote digestion.*

Because of its ability to digest protein, bromelain may alleviate occasional stomach upset and heartburn.* In several animal studies, bromelain inhibited the activity of enterotoxins (protein toxins) and thus reduced the incidence of enterotoxin-initiated diarrhea.* (1,2)

Artichoke Leaf Extract
Artichoke (Cynara scolymus) leaf has been used traditionally as a liver tonic and digestive herb.*

Several human clinical trials, including one multi-center, double-blind, placebo-controlled study, have found that artichoke leaf extract helps relieve symptoms of occasional indigestion — such as pain, nausea, retching and the sensation of fullness — and improves quality of life.* (3,4,5,6) The herb was also shown to normalize elimination in two studies, reducing the incidence of diarrhea and constipation.* (6,7) In fact, 96 percent of treated subjects in one trial rated the extract as good or better than other therapies they had tried. (7)

In vitro research has revealed that artichoke may increase the secretion of bile.* Bile helps break down fats, which can be difficult to digest, possibly explaining artichoke’s positive effect on digestion. (8)

Turmeric Extract
Turmeric, also known Curcuma longa, is a tropical plant native to India and Southeast Asia. It is part of the ginger family. For 4,000 years, turmeric has been used to support digestion and liver health.* (9)

Modern research is confirming turmeric’s traditional use. In a multicenter, randomized, double-blind, placebo-controlled study of people who suffered from occasional indigestion, turmeric proved effective for 87 percent of patients, helping them to experience full or partial relief from digestive discomfort.* (10)

Peppermint Oil
Peppermint has a long history of traditional use for supporting healthy digestion.* At one point in time, it was common practice in Europe to ingest peppermint after eating in order to encourage the digestive process. Hence, the after-dinner mint.

Today, peppermint oil has been studied for its effect on digestion because the oil is a concentrated source of some of peppermint’s most active constituents. Several human clinical trials have confirmed peppermint’s benefits for occasional digestive upset.* (11,12,13,14) One — a randomized, double-blind, placebo-controlled study — reported that among subjects taking peppermint oil, 79% experienced a lessening of abdominal discomfort, 83% had less bloating and better bowel regularity, and 79% were less flatulent.* (13)

Caraway Oil
Caraway is used as a carminative, meaning an herb that relieves occasional gas pain.* Ancient Egyptian and European records indicate that caraway has been used to support digestive health for thousands of years.*

More recently, two multi-center, double-blind, placebo-controlled human studies found that a blend of peppermint and caraway oils provided relief from the stomach discomfort that comes with occasional indigestion.* (14,15)

Digestive Enzyme Blend
The body's natural digestive juices contain active enzymes that facilitate the effective breakdown of food. A common cause of indigestion is a lack of these enzymes. By supplementing with enzymes regularly, the body's ability to digest food properly and painlessly is restored.*

Digestalin includes enzymes to help break down all the different constituents of food, including:

Protein

• Papain, from papaya fruit, acts as a catalyst in the breakdown of proteins
• Pepsin is the primary digestive component of gastric juice
• Acid Stable Protease is a protein-digesting enzyme

Fat

• Lipase assists in the breakdown of fats into glycerol and fatty acids

Carbohydrates

• Amylase breaks down complex carbohydrates such as starch
• Amyloglucosidase breaks glucoside bonds in starch and dextrins to form glucose

Fiber

• Cellulase breaks down cellulose and converts it into glucose
• Hemicellulase is a mixture of enzymes that reduce the bulking effect of fibrous foods

Milk Sugar

• Lactase breaks down lactose (milk sugar) and converts it into glucose

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